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In a small trial of clozapine-treated patients with obesity and with or without T2DM, those who received exenatide compared to usual care experienced more weight loss (4.16 kg more than placebo), as well as greater reductions in BMI, fasting plasma glucose, and hemoglobin A1c (HbA1c) at 24 weeks

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Other than the passive memory decay, Rac1 was also investigated in the active memory forgetting using retroactive interference (RI) and reversal learning and shown to have similar effects as in the passive memory decay (Shuai et al., 2010)