Blood sugar fluctuations (for diabetics) If you are using semaglutide (Ozempic) for managing type 2 diabetes, you need to have stable semaglutide levels in the blood for consistent blood sugar control
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Change in Body Weight (%) from Baseline to Week 72 (Study 8) with WEGOVY 7.2 mg Injection Observed data from in-trial period including imputed data for missing observations (RD-MI)
Common Side Effects (Both Medications) Gastrointestinal Effects (Most Common): Nausea (Zepbound: 25-29%, Wegovy: 24-44%) Diarrhea (Zepbound: 19-21%, Wegovy: 7-30%) Vomiting (Zepbound: 12%, Wegovy: 24%) Constipation (Zepbound: 12-17%, Wegovy: 14-24%) Abdominal pain or discomfort Indigestion and acid reflux General Side Effects: Fatigue or tiredness (approximately 4% of patients) Headache (more common with Wegovy) Dizziness Hair loss (temporary in most cases) Injection Site Reactions: Redness, itching, or bruising at injection site Slightly more common with Zepbound Managing Common Side Effects The good news is that most side effects are: Mild to moderate in severity Most pronounced during the initial weeks of treatment Tend to decrease as your body adjusts to the medication Manageable with proper strategies Practical Tips to Minimize Side Effects: Start Low, Go Slow: Both medications use gradual dose escalation specifically to minimize side effects Dietary Modifications: Eat smaller, more frequent meals
See our Zepbound, Wegovy, Mounjaro, and Ozempic pages for more on each brand
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