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NRT offers a tailored and flexible dosing schedule Nicorette Simple dosing: patch in the morning then a fast-acting format if cravings occur 7 Simple: on-the-go formats that do not need water to take Flexible options: designed to support patient adherence 7 formats to tailor to preferences and lifestyles 17 Monotherapy or combination therapy 17 Can be adjusted to patient taste with a variety of flavours 17 Cytisine/Varenicline/Bupropion: Cytisine : Fixed dosing regimen First 3 days: 1.5mg every 2 hours Days 4-12: 1.5mg every 2.5 hours Days 13-16: 1.5mg every 3 hours Days 17-20: 1.5mg every 5 hours 1 format: tablets Varenicline : Fixed dosing regimen First 3 days: 0.5mg once daily Days 4-7: 0.5mg twice daily Day 8 to end of treatment: 1mg twice daily 1 format: tablets Bupropion : Fixed dosing regimen First 6 days: 150mg daily Day 7 to end of treatment: 150mg twice daily There should be an interval of at least 8 hours between doses 1 format: tablets (immediate or sustained release) To keep in mind: NRT offers a tailored and flexible dosing schedule to support NRT can be continued if relapse occurs and can be tailored to different situations Experiencing a slip-up is normal

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(28) A study published in the Journal of Alternative and Complementary Medicine found that practicing Tai chi significantly increases blood serotonin levels and significantly reduces nicotine dependence, depression and anger