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As of August 8, 2016, the FDA has established new e-cigarette regulations based on the fact that the nicotine present in the device is a byproduct of tobacco

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While most flavorings in e-liquids are designated as generally safe by the FDA for oral consumption in food, those designations do not apply to flavorings used in e-cigarettes as most have not been studied for toxicity when inhaled

In the face of the current Covid-19 pandemic, experts have called on governments and industry leaders to step up controls and increase support for those looking to quit, in a bid to reduce the burden on the already-stressed global healthcare system