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As there is no long-term evidence yet available, the debate about using them as a long-term tobacco harm reduction tool will continue, but this raises the question of what regulation should be in place until we have long-term evidence

As dependence strengthens, the brain requires more nicotine to achieve the same pleasurable effects, increasing the frequency and quantity of use

[116] The website was funded by the conservative activist Foster Friess

In some countries, tobacco is heavily taxed, so purchasing cigarettes at the airport duty-free store can often be one of the best deals in the game (just be sure to check your country's duty-free import allowance)