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While GLP-1 drugs are not designed to target inflammation directly, they may have some anti-inflammatory effects, which could be beneficial

Incretins, including GLP-1RAs, are also useful in patients who cannot tolerate the gastrointestinal (GI) side effects of metformin

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Hypertension has been increasingly recognized as a potential risk factor for reduced bone mineral density and osteoporotic fractures, potentially through shared pathophysiological pathways such as chronic inflammation, oxidative stress, and impaired calcium metabolism