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Beyond its role in actin dynamics, it also moonlights as a transcriptional modulator of nitric oxide synthase pathways, angiogenesis, proliferation, and immuno-inflammation: it attenuates NF-B and TLR , reduces cytokines such as TNF- and IL-6 , and activates PI3K/Akt/eNOS , Notch , and Ang1/Tie2

[DOI] [PubMed] [Google Scholar] 148.Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al

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