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GLP-1 receptor agonists: new treatment frontiers Given the early success of treating diabetes and obesity with glucagon-like peptide-1 receptor agonists (GLP-1RAs) and their neurobiological effects, interest is mounting in identifying new clinical applications and repurposing of these drugs for the treatment of neuropsychiatric conditions

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autonomic sympathetic neurons , brain tissue & and transports monoamines (dopamine, norepinephrine, serotonin & histamine) from the cytoplasm into presynaptic storage vesicles Binds to the same site on VMAT1 & 2 as intracellular monoamines, producing a strong long-lasting inhibition of monoamine (e.g

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