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A direct comparison of the percentage increase in absolute lifetime risk of all alcohol and tobacco-related cancers for smoking ten cigarettes per week, or drinking ten units of alcohol per week revealed that low levels of smoking carried the greatest risk for men (2.1% AR per ten cigarettes, 1.0% AR per ten units of alcohol), with the risk spread throughout the smoking-related cancers

In other words, the exposure to smoke and vape significantly boosted the bacterias inflammatory tendencies

They produce a rough surface lining the artery, which stimulates the formation of blood clots