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By comparison of the total amount of excreted nicotine with the total amount of nicotine in the pinch per time unit, it has been concluded that only 10-20 % of the nicotine originally present in the pinch is absorbed via the buccal mucosa and reaches the systemic circulation (Andersson et al., 1994

If a smoker can stay away from the highly addictive habit for up to a decade, Jha and colleagues say they can hope to live nearly as long as someone who has never picked up a cigarette in their life

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