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In addition, essential proteins such as proteins 53 (P53) and heat shock proteins (HSP70) that play crucial roles in cellular repair and metabolic pathways have notably been downregulated when exposed to e-cigarette vapour

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EPA cannot assure the results of the safety testing are representative of all DIY air cleaners in all scenarios because there is a wide range of variability in the materials used and how the air cleaners can be built or operated