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doi: 10.1073/pnas.1108220109 69 PongkanWPintanaHSivasinprasasnSJaiwongkamTChattipakornSCChattipakornN

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For semaglutide (Ozempic) used in type 2 diabetes: Starting dose: 0.25 mg once weekly for 4 weeks Maintenance dose: Increase to 0.5 mg weekly

Despite their potential, polyphenols remain underutilized in functional foods and dietary supplements due to several physicochemical properties, including low epithelial permeability, poor solubility in gastrointestinal fluids, structural modifications during digestion, and limited oral bio-accessibility (128, 129)