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In response to increasingly stringent restrictions on tobacco advertising, promotions, and sales, tobacco companies have turned to other novel marketing tactics such as flavor descriptors or flavor imagery, to appeal to target audiences [41]

Similar content being viewed by others Introduction Larynx cancer is one of the most prevalent malignancies within the head and neck region, significantly impacting global health

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The FDA has specifically named Juul as a company whose marketing practices concern them

In ApoE-deficient mice fed a high-fat diet, nicotine amplified atherosclerotic lesions and increased inflammatory cytokines, possibly through ROS-NLRP3-mediated endothelial cell pyroptosis 54) , as nicotine activated NLRP3 through ROS, leading to pyroptosis as well as IL-1 and IL-18 production in human aortic endothelial cells 54)