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In addition, SS-31 inhibited the activation of the NF- B signaling pathway [42]

The weekly dosing schedule makes adherence straightforward compared to daily medications, and the long half-life ensures consistent blood levels throughout the week

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To overcome these obstacles, new strategies for oral delivery of biomacromolecules have been developed, such as the use of permeation enhancers (PEs), protease inhibitors and nanoparticle-based delivery systems [6,7]

April 22, 2026