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"Cigarette smoke consists of numerous compounds that are harmful, and it has been linked to a reduction in the thickness of layers in the brain , and to brain lesions, involving areas such as the frontal lobe, which plays a role in voluntary movement and control of thinking, and a decrease in activity in the area of the brain that processes vision," he said

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It is not based on health, safety, or reduced-risk claims, and it does not imply that one combustible cigarette is safer than another