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Studies (81, 82) have revealed that NOR can stably bind to AhR, promote AhR/Hsp90 dissociation and AhR nuclear translocation, increase the accumulation of AhR-ARNT complex, activate AhR-mediated reporter gene and up-regulate the expression of CYP1A1

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J Biol Chem 268:1961019617 Beuve N, Rispail N, Laine P, Cliquet JB, Ourry A, Le Deunff E (2004) Putative role of -aminobutyric acid (GABA) as a long-distance signal in up-regulation of nitrate uptake in Brassica napus L

Side Effects and How They Are Managed Side effects of Qsymia may include dry mouth, mild tingling sensations, altered taste, constipation, or difficulty sleeping if taken too late in the day