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Oxaloacetate treatment for mental and physical fatigue In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long-COVID fatigue patients: a non-randomized controlled clinical trial

It requires more operational lift upfront, but at scale it's one of the highest-leverage decisions in the compounding care model

Ravn-Haren G, Olsen A, Tjnneland A, Dragsted LO, Nex BA, Wallin H, et al

This works by temporarily blocking nerve signals to the muscles which will prevent the facial muscles from contracting when making expressions

[,,] Through various redox processes, mitochondria are essential for producing ATP, which in turn causes the cell to produce ROS and oxidative dysfunction