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Natural mouthwashes, as opposed to commercial ones that may contain alcohol, can be effective

Vardavas CI, Anagnostopoulos N, Kougias M, Evangelopoulou V, Connolly GN, Behrakis PK (2012) Short-term pulmonary effects of using an electronic cigarette: impact on respiratory flow resistance, impedance, and exhaled nitric oxide

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How Carcinogens in Cigarette Smoke Cause Lung Cancer The carcinogens in cigarette smoke that are inhaled can be metabolically activated (most notably by cytochrome P450 enzymes in the liver) to intermediate compounds that covalently or (sometimes) directly bind to DNA