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These chemicals are major constituents of coal tar 64 and found to be cytotoxic 65,66

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The absence of elevated CRP levels and the lack of clinical signs suggestive of infection led us to rule out infectious etiologies

The absence of significant effects of caffeine administration on LV long-axis indices observed in this study confirms early reports that found no effects on standard indices of LV systolic and diastolic function [26], and strengthens this hypothesis by showing that functional changes after caffeine assumption cannot be detected even when sensitive indices of ventricular function are considered

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