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Together, all these biochemical facts represent a mechanistic construal reflecting a solid scaffold for the alleged beneficial cardiovascular outcomes obtained by inhibition of DPP4 activity

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Mingrone G, Panunzi S, De Gaetano A, et al

Peptide therapy begins with an individualized evaluation to ensure safety and effectiveness

Table 6: Results at Week 52 in a Trial Comparing TRESIBA to Insulin Glargine U-100 (Study A) and Week 26 in a Trial Comparing TRESIBA to Insulin Detemir (Study B) in Adult Patients with Type 1 Diabetes Mellitus Receiving Insulin Aspart at Mealtimes Study C TRESIBA Administered at the Same Time Each Day or at Any Time Each Day in Combination with a Rapid Acting Insulin Analog at Mealtimes in Adult Patients The efficacy of TRESIBA was evaluated in a 26 week randomized, open label, multicenter trial in 493 patients with type 1 diabetes mellitus