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The rate of malignant transformation (often given as 1% every 5 years) is controversial because some studies do not correct for confounding factors such as smoking, while other included erythroleukoplakias, leukoplakias (diagnosed as plaque-type LP), and proliferative leukoplakia in the group of lichenoid lesions

To view a copy of this licence, visit About this article Cite this article Enomoto, Y., Imai, R., Nanjo, K

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