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A surrogate result is weaker evidence than an outcome result

Increased level of CD44 enables self-renewal and is also associated with metastasis and poor prognosis

Eack et al., Schizophrenia Research , 2010;120:210-216) have shown CET effects to persist for at least an additional year following treatment

Second, information about the localization of the drug target in the brain, which can be extra- or intracellular, as well as functional expression of the selected transporter in the brain is essential for the selection of relevant transporter to be targeted at the BBB and brain parenchymal cells

It is ubiquitous in living systems