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Combining measurements of hemolysis and ultra-high-throughput metabolomics, we report that storage of RBCs, independent of storage temperature, in alkaline additive E-Sol5 has beneficial effects that include increased activation of glycolysis, the PPP and glutathione homeostasis, ultimately preserving high energy adenylate pools better than SAGM

Ensure that they have valid credentials/licenses necessary for performing safely any surgical procedure associated with glutathione injections

During this process, ATP is broken down into adenosine diphosphate (ADP) and inorganic phosphate (P i )

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