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351 In the process of ferroptosis, cells are affected by oxidative stress and lipid peroxidation, resulting in the rupture of cell membranes and cell death, which is manifested mainly by the reduction in GPX4, the core enzyme of the antioxidant system (glutathione system), and the high expression of the lipid peroxidation marker 4-HNE

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PKA might then phosphorylate a range of target proteins, setting off subsequent cellular reactions

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Analysts said those results were comparable to outcomes often seen with bariatric surgery