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Funding for this research was provided by the National Institutes of Health (R21ES014947, R01ES016772, K01CA104517, K24DA023464, P01ES022831), the Environmental Protection Agency (RD-83543701), the National Cancer Institute (R01CA239595), the Duke Comprehensive Cancer Center (ACS-IRG 83-006) and VCU Massey Cancer Center (P30 CA016059)

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