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E.CsiszarA.2mediated antioxidant response Am J Physiol.2011H363-H372

D.van RosmalenJ.GroeneveldG

After 48 h transfection, cells were harvested for subsequent experiments

These challenges stem from an incomplete understanding of glaucomatous optic neuropathy and retinopathy, which can be divided into several areas: the mechanisms of pathogenesis remain uncertain, therapeutic targets are not clearly defined, and there is a lack of validated preclinical models (98, 99)