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sites Weekly subcutaneous dosing (19 mg or titrated regimens) Results at 48 weeks: 1 mg 9.2% mean weight change 3 mg 12.0% 6 mg 17.7% 9 mg 20.2% Placebo 0.4% Safety Profile: Dose-related nausea (1164%) and fatigue (046%), mostly mild-to-moderate

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575:693698 Bersuker K, Hendricks JM, Li Z, Magtanong L, Ford B, Tang PH, Roberts MA, Tong B et al (2019) The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

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