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Archived from the original on December 31, 2014

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The metabolic disorder of UA mainly linked with abnormal urate transporters is an important cause of many diseases

The Baltimore Longitudinal Study of Aging, investigating a total number of 669 individuals with an average age of 67 years, showed that participants with lower mitochondrial oxidative capacity exhibited hallmarks of inflammation, specifically showing markedly higher levels of interleukin-6 and C-reactive protein, as well as increased erythrocyte sedimentation rate compared with participants with better oxidative capacity, independent of age and sex (Zampino et al., 2020)

GLP-1 agonism is a mechanism of action typically not used by these drugs, and in the context of Eriomin, it appears to be a relatively safe mechanism, as no significant adverse effects were reported in this study or the other clinical study