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Other harmful health effects of smokeless tobacco include: Heart disease and high blood pressure Increased risk of heart attack and stroke Increased risk of early delivery and stillbirth when used during pregnancy Smokeless tobacco causes nicotine addiction

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Overall, while both pipe tobacco and cigarette tobacco are tobacco products, they have distinct differences in terms of cut, moisture, flavor, additives, and nicotine content

[8] Pryor and Stone determined that 1 g of tar from cigarette smoke contains more than 1017 long-lived free radicals (hours to months), while 1 g volatile fraction of smoke contains 1015 short-lived free radicals (seconds)