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Patients with LPP, often considered to be a variation of patch stage CTCL, present with atrophic, inflammatory lesions, primarily over the buttocks and intertriginous areas

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BULKING IN TOBACCO Tobacco should not be removed from the curing facility until all the stems (midribs) of the leaves have dried to a firm condition (not "fat" or "mushy") Growers should constantly check the bulk to ensure that tobacco is not heating from bacterial growth where moisture levels are too high (bulk rotation) High moisture leads to development of Tobacco-specific Nitrosamines (TSNAs) a potential carcinogen Be sure to use good judgement to avoid excessive moisture, which lead to rejection at delivery and increased TSNA