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It further suppresses the NF-B and MAPK signaling pathways, leading to decreased inflammatory cytokine levels [76]

Is it possible that neurosteroids, such as pregnanolone sulfate and its synthetic analog pregnanolone hemisuccinate, which negatively modulate glutamatergic neurotransmission, may also have potential therapeutic applications in AD and age-related MCI

This dual role in enhancing immune responses and promoting tolerance highlights DPP4s significance in the immune system and its potential as a target for treating various immune-related conditions