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14 , 15 Based on emerging data suggesting that targeting the glucagon receptor may exert direct kidney protective effects, 16 we performed an exploratory analysis of these 2 clinical trials to assess the association of retatrutide treatment with changes in kidney parameters in these 2 patient populations

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doi: 10.3390/jcm11061574 145 Novell-AlsinaREsteba-CastilloSCaixsAGabauEGimnez-PalopOPujolJet al

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During DN, the increased expression of JAK in glomerular podocytes aggravates the persistent inflammatory response of the kidney by activating the STAT3/NF-B pathway