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Time reported on a 2024 study of nicotine pouch users which found almost all had reported some kind of unpleasant side-effect including mouth lesions, nausea and a sore throat or mouth
It is defined as "essentially an oral mucosal white/gray lesion that cannot be considered as any other definable lesion." Oral leukoplakia is a gray patch or plaque that develops in the oral cavity and is strongly associated with smoking
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But they make me hopeful
Tree tobacco contains lower concentrations of nicotine but does have high concentrations of anabasine, which acts similarly to nicotine in the body and is also poisonous
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