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IQOS, which is a type of heated tobacco product, offers an alternative to smoking that still uses real tobacco to deliver nicotine

Forty male and 40 female Fischer 344 rats at 5 weeks of age were divided into groups of 10 male and 10 female rats and exposed to either filtered air (Air Control) or 75, 200 or 400 mg total particulate matter (TPM)/m 3 of diluted cigarette smoke generated from 3R4F Kentucky Reference Research Cigarettes

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Plot-driven or something more sinister