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The trial did not achieve its primary endpoint of demonstrating non-inferiority on weight loss for CagriSema compared to tirzepatide after 84 weeks, reads a Novo Nordisk press release
Start slowly and gradually: Use LHA 2-3 times a week, preferably in the evening
DSIP administration did not significantly affect corticotropin-releasing-hormone (CRH)-stimulated or meal-induced ACTH and cortisol secretion, indicating thatcontrary to stress-protective effects reported in some animal studiesDSIP does not measurably blunt the human cortisol response
Lushchak, 2012
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