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These include polynuclear hydrocarbon benzo[a]pyrene (a chemical found in coal tar and tobacco smoke), nicotine, and tobacco-specific N-nitrosamines that are linked to cancers of the food pipe, stomach, and mouth

Lifestyle and anthropometric risk factors for prostate cancer in a cohort of Iowa men

These include nicotine addiction and the associated health problems such as heart disease and lung cancer

In response to the FDA authorization, multiple organizations, including the Campaign for Tobacco-Free Kids, American Cancer Society Cancer Action Network, American Heart Association, American Lung Association and Truth Initiative, issued a joint counterstatement, arguing the authorization puts youth and the publics health at risk