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And paying this much money (they can cost $12,000 a year or more without insurance coverage) to inject yourself with a hormone every Tuesday is a pretty drastic decision

The three mechanisms are: (1) slowed gastric emptying paired with a bile acid surge, (2) direct GIP/GLP-1 receptor activation in the intestine itself, and (3) a rebalancing gut microbiome

Ozempic is safe and effective when used as indicated for the treatment of adults with type 2 diabetes to lower blood sugar, along with diet and exercise, reduce the risk of major cardiovascular events such as heart attack, stroke, or death in adults with type 2 diabetes who also have heart disease, and lower the risk of worsening kidney disease, kidney failure (end-stage kidney disease), and death due to cardiovascular disease in adults with type 2 diabetes who also have chronic kidney disease

doi: 10.1016/j.molmet.2019.11.018 187 AdriaenssensAEGribbleFMReimannF

If a weight loss medication is on Aetnas formulary, a prior authorization may be required for its coverage