semaglutide lactation While Breastfeeding: Is It Safe? Allegra Gast | Functional Dietitian

This comparison is particularly relevant in the context of polypharmacy a common scenario in modern medicine where patients are often prescribed multiple drugs

Unlike the natural GLP-1 hormone, semaglutide is a modified analog with non-natural amino acid substitutions at positions 7 and/or 8, which improve its stability and resistance to enzymatic breakdown

Canada added the cardiovascular label in 2024, and provincial formularies followed by mid-2025, expanding patient eligibility

Early preclinical studies suggested GLP-1 receptor expression in thyroid C cells, forming the basis for rodent findings of C-cell hyperplasia and medullary thyroid carcinoma under chronic GLP-1RA exposure [47,48]

Dont take the tablets if you are allergic to Semaglutide