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An in vitro assay using epithelial cells (AMOL-III) from the oral leukoplakia of a Khaini user and treatment with aqueous extract of Khaini showed alteration in the expression of proteins involved in cell cycle regulation and DNA methylation, suggesting the role of Khaini in oral carcinogenesis (Rohatgi et al., 2005)

Nutrients 13(11):4117 Prezioso D, Strazzullo P, Lotti T, Bianchi G, Borghi L, Caione P et al (2015) Dietary treatment of urinary risk factors for renal stone formation

Indeed, smoking is heavily contributing to the progression of such long-term diseases, including cardiovascular and respiratory 5

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A clinician will apply small drops of different allergens to parts of your skin (often your forearm) and wait to see which allergens produce a reaction on your skin