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Cytotoxic effects of heated tobacco products (HTP) on human bronchial epithelial cells

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Of the four studies, three were RCTs477, 478, 479 and one was a non-randomized study (NRS) that included a post-hoc analysis of users of liquid-based e-cigarettes.245, 480 Regarding smoking cessation success rates, intervention groups who received smoking cessation treatment showed significantly higher quit rates than control groups

The warnings came a year-and-a-half after Surgeon General Luther Terry announced the findings of a groundbreaking study: "It is the judgment of the Committee that cigarette smoking contributes substantially to mortality from certain specific diseases and to the overall death rate." The warning labels were a warning shot across the bow for an industry that for years had entrenched itself in both our national economy and popular culture

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