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Diabetes Ther 12 (1), 143157 (2021)

Here are the most common mistakes: Shaking the Vial: We mentioned it before, but it bears repeating

Crucially, no liver safety signals were reported a significant detail after Pfizer recently halted development of its oral GLP-1 candidate, danuglipron, due to liver toxicity concerns

Serious side effects (rare but important) Pancreatitis

Pica behavior is a validated endpoint to assess the ability of a compound to induce nausea/malaise in non-vomiting species, as mouse, based on the monitoring of non-nutritive (kaolin) food intake, as an index of gastrointestinal discomfort 43,44