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Taylor and Francis+NEJM , doi:10.1080/096374080410001666504

levothyroxine, lisinopril, metformin, and sitagliptin (BCS Class III)

The glucagon-like peptide-1 receptor-agonist semaglutide

Both immediate-release exenatide (Byetta) and extended-release exenatide (Bydureon BCise) have established gastrointestinal side effect profiles, though they are less commonly prescribed today due to the availability of more convenient once-weekly alternatives

Clinical data reveals that without proper resistance training and intentional nutrition, 25% to 40% of the weight lost on these medications can come directly from lean skeletal muscle and bone density