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Rhoades most popular characters, Cig Mom and Beer Dad (based on her father), often touch on dark comedy, with one of her highest performing sketches being POV: Back to School Shopping with Your Cig Mom, earning 2.9 million likes

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Acrosin is a proteolytic enzyme that is released by the sperm when it comes into contact with an ovum, degrading the zona pellucida of the oocyte and allowing the sperm to penetrate it [91]