L., Magnusson, I., Katz, L
Lipidation transforms LC3-I (nascent and cytosolic) to LC3-II (conjugated to PE and attached to the autophagosome) (65, 68) ( Figure 1 , panel 3)
Additionally, genetic variants in the phosphodiesterase 8B ( PDE8B ) gene, which encodes a high-affinity cAMP-specific phosphodiesterase, as genetic modulators of TSH levels (30, 31), and in the TSH receptor (32) may also influence the setpoint of the HPT axis, potentially contributing to diminished cellular responsiveness to circulating thyroid hormones
An essential component in an NADPH pathway that prevents cellular components from being oxidized
Decreased IL-8 level is believed to reduce endometrial stromal cell viability [153]