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Characteristics of included studies Data were collected from six different databases, primarily based in the United States 23-26, 28-33 , with the exception of one study 27 , which used data from the Korean National Health Insurance Service (Table 1)

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Step 7: Drill Necessary Holes Airway and Mouthpiece: Drill an airway hole in the bowl and a mouthpiece hole in the stem, ensuring proper alignment and size

INTRODUCTION Smoking and other forms of tobacco or nicotine use, including the use of e-cigarettes, induce biomarkers of cardiovascular disease (CVD) risk 1