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Dehydroascorbate (DHA), an oxidant, is formed from ascorbic acid during the removal of ROS, yet the enzyme responsible for converting DHA back to ascorbic acid is dependent on GSH

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DDI2 is a ubiquitin-directed endoprotease responsible for cleavage of transcription factor NRF1

These activated T cells then proliferate and release inflammatory factors, triggering insulitis - a process characterized by inflammation of the pancreatic islets