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Conventional methods tend to lose effectiveness due to resistance to known drugs, a decrease in tumor selectivity, and solubility
Interestingly, another monoclonal LPL antibody, 4-1a (Millipore, MABS1270) at 1:5000 dilution, which binds to the N-terminal fragment of LPL, did not detect crosslinked LPL on these blots, although uncrosslinked controls were detected
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It mimics the natural hormone GLP-1 to support appetite regulation, blood sugar balance, and fullness signals
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