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Blockade of macrophage autophagy ameliorates activated lymphocytes-derived DNA induced murine lupus possibly via inhibition of proinflammatory cytokine production

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In a secondary sulfur metabolic pathway, APS phosphorylation catalyzed by APS kinases (APK) forms phosphoadenosine 5-phosphosulfate (PAPS) (Takahashi et al., 2011)

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Homocysteine can then be converted back to methionine or transformed in other pathways