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Bupropion is an antidepressant, and for patients with mild-to-moderate depression alongside obesity, Contraves bupropion component may offer a secondary benefit on mood

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[11] [12] This delayed gastric emptying is a key therapeutic effect that helps control postprandial glucose excursions and promotes feelings of fullness

Informed by Robust Clinical Literature : Phase 1b, phase 2, and phase 3a programs have generated substantial data in obesity and type 2 diabetes research populations, helping guide mechanistic and translational study design

The authors also highlight the safety of repeated intranasal use and encourage long-term studies assessing neurodegeneration and synaptic health