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The compound was registered in Russia as a research peptide and was the subject of an extensive in-house programme through the 1990s and 2000s

Although ferroptosis is considered immunogenic and capable of inducing the release of DAMPs to activate antitumor immune responses, recent studies have shown that ferroptosis inducers may suppress the function of CD8 + T cells and NK cells under certain conditions, thereby reducing the efficacy of immunotherapy

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Western blot Cell and heart samples were lysed in RIPA buffer supplemented with protease and phosphatase inhibitors (Complete Mini, Roche and Halt Phosphatase Inhibitor Cocktail, ThermoFisher)